منابع مشابه
Heteropolymer translocation through nanopores.
The authors investigate the translocation dynamics of heteropolymers driven through a nanopore using a constant temperature Langevin thermostat. Specifically, they consider heteropolymers consisting of two types of monomers labeled A and B, which are distinguished by the magnitude of the driving force that they experience inside the pore. From a series of studies on polymers with sequences AmBn...
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Threading charged polymers through a nanopore, driven by electric fields E, is investigated by means of Langevin dynamics simulations. The mean translocation time 〈τ〉 is shown to follow a scaling law Nα, and the exponent α increases monotonically from 1.16(4) to 1.40(3) with E. The result is double-checked by the calculation of mean square displacement of translocation coordinate, which asserts...
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Given a polygonal channel between obstacles in the plane or in space, we present an algorithm for generating a parametric spline curve with few pieces that traverses the channel and stays inside. While the problem without emphasis on few pieces has trivial solutions, the problem for a limited budget of pieces represents a nonlinear and continuous (‘infinite’) feasibility problem. Using tight, t...
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Nanopores are emerging as powerful tools for the detection and identification of macromolecules in aqueous solution. In this review, we discuss the recent development of active and passive controls over molecular transport through nanopores with emphasis on biosensing applications. We give an overview of the solutions developed to enhance the sensitivity and specificity of the resistive-pulse t...
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ژورنال
عنوان ژورنال: Journal of Biological Physics
سال: 2012
ISSN: 0092-0606,1573-0689
DOI: 10.1007/s10867-012-9289-1